35+ Top Health Tech Seed Funds - The Definitive List for 2026

This is a definitive and well-researched list of top health tech seed venture capital investors according to data.

April 8, 2026

About Beta Boom

Beta Boom is pre-seed and seed fund invsting in founders who defy the mainstream.

This list highlights the most active U.S.-based seed-stage venture capital firms investing in healthcare in 2026, helping founders identify the right early-stage partners in a rapidly evolving market.

To ensure relevance and usefulness, we applied a focused screening methodology. Each firm included in this list meets the following criteria:

Actively invests in healthcare sectors such as telehealth, electronic health records (EHR), health diagnostics, personal health, mental health, mHealth, and home healthcare
Has made recent healthcare investments between 2025 and 2026
Focuses on seed-stage or early-stage investments
Has completed at least 10 total investments, indicating consistent deployment of capital

This approach ensures that all listed investors are not only active today but also experienced in backing early-stage healthcare startups.

All data in this list is sourced from Crunchbase.

Now, let’s take a look at the top seed-stage venture capital firms actively investing in healthcare startups.

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‍Frist Cressey Ventures

Frist Cressey Ventures is a venture capital firm dedicated to transforming healthcare and improving lives. Beyond capital, the firm provides strategic support to help companies scale, innovate, and drive meaningful, system-wide change in healthcare.

Healthcare Investment Focus: 100%
Seed Investment Activity: 8.33%
Total Healthcare Investments: 60
Most Recent Healthcare Investment: March 25, 2026
Website: https://fcventures.com/

Health Velocity Capital

We invest exclusively in innovative healthcare software and services businesses. We’re an investment firm that is driven by purpose, a clear mission, and an important set of core values. Our mission is to generate outstanding financial returns while being the preferred innovation partner of entrepreneurs and investors working toward a more affordable, sustainable, consumer-friendly healthcare system.

Healthcare Investment Focus: 100.00%
Seed Investment Activity: 3.03%
Total Healthcare Investments: 33
Most Recent Healthcare Investment: February 26, 2026
Website: https://www.healthvelocitycapital.com/

W Health Ventures

We are an investment firm focused on building generational healthcare companies from scratch in India, US and beyond.

Healthcare Investment Focus: 100.00%
Seed Investment Activity: 31.58%
Total Healthcare Investments: 19
Most Recent Healthcare Investment: January 27, 2026
Website: https://www.whealthventures.com/

Town Hall Ventures

We partner with founders who are solving long-standing healthcare challenges for underserved communities.

Healthcare Investment Focus: 98.15%
Seed Investment Activity: 13.21%
Total Healthcare Investments: 53
Most Recent Healthcare Investment: March 25, 2026
Website: https://www.townhallventures.com/

Waterline Ventures

Waterline invests in early growth technology and service-enabled technology companies in the healthcare space.

Healthcare Investment Focus: 97.44%
Seed Investment Activity: 31.58%
Total Healthcare Investments: 38
Most Recent Healthcare Investment: July 14, 2025
Website: https://waterlineventures.com/

Headwater Ventures

Headwater backs preseed and seed teams building the infrastructure and intelligence that make care administratively simpler, clinically safer, and financially legible.

Healthcare Investment Focus: 96.88%
Seed Investment Activity: 64.52%
Total Healthcare Investments: 31
Most Recent Healthcare Investment: December 11, 2025
Website: https://www.headwater.vc/

SteelSky Ventures

At SteelSky, we accelerate bold innovations shaping the future of healthcare. In just 5 years, we've built a portfolio valued at over $10B, driving substantial revenue and improving outcomes for over 45 million people globally.

Healthcare Investment Focus: 96.30%
Seed Investment Activity: 42.31%
Total Healthcare Investments: 26
Most Recent Healthcare Investment: November 6, 2025
Website: https://steelskyventures.com/

Hopelab

Our mission is to advance the mental health and well-being of young people through uncovering knowledge and evidence, investing in innovators, and funding youth-centered solutions.

Healthcare Investment Focus: 94.12%
Seed Investment Activity: 37.50%
Total Healthcare Investments: 16
Most Recent Healthcare Investment: November 21, 2025
Website: http://hopelab.org/

Optum Ventures

Investing in extraordinary entrepreneurs to transform healthcare together.

Healthcare Investment Focus: 93.07%
Seed Investment Activity: 3.19%
Total Healthcare Investments: 94
Most Recent Healthcare Investment: March 10, 2026
Website: https://www.optumventures.com/

Avestria Ventures

Avestria invests in women’s health and female-led life science ventures. We define women’s health as conditions affecting women exclusively (such as menopause), differently (such as cardiovascular disease), or disproportionately (such as Alzheimer’s).

Healthcare Investment Focus: 90.91%
Seed Investment Activity: 25.00%
Total Healthcare Investments: 20
Most Recent Healthcare Investment: September 3, 2025
Website: https://www.avestria.vc/

HealthX Ventures

We back entrepreneurs creating value with digital health solutions.

Healthcare Investment Focus: 90.38%
Seed Investment Activity: 46.81%
Total Healthcare Investments: 47
Most Recent Healthcare Investment: March 3, 2026
Website: https://www.healthxventures.com/

SpringTide Ventures

We lead early-stage financings for tomorrow's greatest healthcare companies.

Healthcare Investment Focus: 90.00%
Seed Investment Activity: 52.78%
Total Healthcare Investments: 36
Most Recent Healthcare Investment: August 14, 2025
Website: https://www.springtide.com/

Penn Medicine Co-Investment Program

Assists faculty entrepreneurs as they move along the path to venture creation and permanent financing through active support and early stage targeted co-investments focused on cell therapy, gene therapy, mRNA, lipid nanoparticles, and connected health technologies.

Healthcare Investment Focus: 87.50%
Seed Investment Activity: 35.71%
Total Healthcare Investments: 14
Most Recent Healthcare Investment: January 1, 2025
Website: https://pci.upenn.edu/penn-medicine-co-investment-program-launches/

Seae Ventures

We invest in companies providing direct community care, leveraging virtual technologies for broader access, and strengthening infrastructure through better data and predictive analytics. Our goal is a portfolio of great breadth and depth.

Healthcare Investment Focus: 86.96%
Seed Investment Activity: 50.00%
Total Healthcare Investments: 20
Most Recent Healthcare Investment: January 7, 2025
Website: https://seaeventures.com/

Ajax Health

Ajax Health deploys capital and leverages operational experience to accelerate healthcare innovation across medical devices, digital health, healthcare services and biotechnology.

Healthcare Investment Focus: 86.67%
Seed Investment Activity: 7.69%
Total Healthcare Investments: 13
Most Recent Healthcare Investment: September 3, 2025
Website: https://ajaxhealth.com/

UPMC Enterprises

Transforming  ideas into thriving  businesses and Life Changing Medicine.

Healthcare Investment Focus: 86.36%
Seed Investment Activity: 7.89%
Total Healthcare Investments: 38
Most Recent Healthcare Investment: March 18, 2026
Website: https://enterprises.upmc.com/

Sonder Capital

Investing in innovative technologies to create a new standard of care.

Healthcare Investment Focus: 85.71%
Seed Investment Activity: 16.67%
Total Healthcare Investments: 12
Most Recent Healthcare Investment: March 10, 2026
Website: https://sondercapital.com/

Wavemaker 360

We invest in healthcare disruptors – the entrepreneurs that see how the industry is transforming itself and want to make a big difference.

Healthcare Investment Focus: 84.62%
Seed Investment Activity: 81.82%
Total Healthcare Investments: 66
Most Recent Healthcare Investment: February 1, 2025
Website: https://www.wavemaker360.com/

Catalyst Health Ventures

We work closely with medical technology (MedTech) entrepreneurs to provide the resources, mentorship and connections needed to navigate the complexities of healthcare.

Healthcare Investment Focus: 84.44%
Seed Investment Activity: 5.26%
Total Healthcare Investments: 38
Most Recent Healthcare Investment: April 22, 2025
Website: https://chv.vc/

Rock Health Capital

We invest in remarkable entrepreneurs working at the intersection of healthcare and technology.

Healthcare Investment Focus: 84.21%
Seed Investment Activity: 85.42%
Total Healthcare Investments: 96
Most Recent Healthcare Investment: November 17, 2025
Website: https://rockhealthcapital.com/

PFM Health Sciences

Is a leading healthcare investment advisor currently managing public and private investments. The firm led by Founding Partner and CIO, Brian Grossman, is focused on partnering with innovative biopharma, medical technology, life science and healthcare service companies.

Healthcare Investment Focus: 82.61%
Seed Investment Activity: 0.00%
Total Healthcare Investments: 19
Most Recent Healthcare Investment: January 7, 2026
Website: https://www.pfmhealthsciences.com/

SpringRock Ventures

By partnering with us, you work with an experienced investment team with co-founder experience; seasoned in the undulations a start-up undergoes between its founding and its ultimate success.

Healthcare Investment Focus: 82.50%
Seed Investment Activity: 48.48%
Total Healthcare Investments: 33
Most Recent Healthcare Investment: September 4, 2025
Website: https://springrockventures.com/

Meridian Street Capital

We help turn the best ideas in healthcare into category-defining companies.

Healthcare Investment Focus: 82.22%
Seed Investment Activity: 48.65%
Total Healthcare Investments: 37
Most Recent Healthcare Investment: August 14, 2025
Website: https://msc.vc/

LRVHealth

The healthcare venture capital platform connecting the largest strategic network of leading healthcare organizations with the entrepreneurs addressing the industry's biggest challenges and opportunities.

Healthcare Investment Focus: 82.11%
Seed Investment Activity: 6.41%
Total Healthcare Investments: 78
Most Recent Healthcare Investment: March 3, 2026
Website: https://www.lrvhealth.com/

HLM Venture Partners

HLM only invests in healthcare. Our careful study of this complex and highly regulated sector allows us to spot and overcome potential pitfalls with precision.

Healthcare Investment Focus: 81.62%
Seed Investment Activity: 1.80%
Total Healthcare Investments: 111
Most Recent Healthcare Investment: December 17, 2025
Website: https://www.hlminvestmentpartners.com/

The Vertical Group

A venture capital firm that is focused on the fields of medical technology and biotechnology.

Healthcare Investment Focus: 81.16%
Seed Investment Activity: 7.14%
Total Healthcare Investments: 56
Most Recent Healthcare Investment: March 12, 2025
Website: https://www.vertical-group.com/

Supermoon Capital

Venture capital for the scientists, technologists, and creatives building the future of sleep and sleep-adjacent categories.

Healthcare Investment Focus: 80.00%
Seed Investment Activity: 33.33%
Total Healthcare Investments: 12
Most Recent Healthcare Investment: February 27, 2026
Website: https://supermooncapital.com/

GreyMatter

Unlocking breakthrough progress in mental health.

Healthcare Investment Focus: 80.00%
Seed Investment Activity: 35.00%
Total Healthcare Investments: 20
Most Recent Healthcare Investment: February 23, 2026
Website: https://www.greymattercapital.com/

Santé Ventures

Santé invests at the forefront of healthcare and technology innovation, managing over $1 billion in capital.

Healthcare Investment Focus: 79.28%
Seed Investment Activity: 5.68%
Total Healthcare Investments: 88
Most Recent Healthcare Investment: February 4, 2026
Website: https://sante.com/

Aberdare Ventures

Aberdare Ventures is a venture firm that focuses on a limited number of entrepreneurial teams committed to building leading healthcare technology companies.

Healthcare Investment Focus: 78.08%
Seed Investment Activity: 8.77%
Total Healthcare Investments: 57
Most Recent Healthcare Investment: June 1, 2025
Website: https://aberdare.com/

Coyote Ventures

Democratizing healthcare access for overlooked populations through innovation.

Healthcare Investment Focus: 76.92%
Seed Investment Activity: 70.00%
Total Healthcare Investments: 10
Most Recent Healthcare Investment: March 12, 2026
Website: https://www.coyote.ventures/

SeedToB Capital

AI is transforming the world, and we believe its applications in healthcare have unmatched potential for impact.

Healthcare Investment Focus: 76.19%
Seed Investment Activity: 50.00%
Total Healthcare Investments: 16
Most Recent Healthcare Investment: June 3, 2025
Website: https://seedtob.com/

Virtue

Virtue is the earliest stage healthcare venture capital firm. We back elite founders at the earliest stage to radically transform our healthcare ecosystem and typically invest $500K - 4M in our initial check.

Healthcare Investment Focus: 75.00%
Seed Investment Activity: 66.67%
Total Healthcare Investments: 15
Most Recent Healthcare Investment: March 11, 2026
Website: https://www.virtuevc.com/

FCA Venture Partners

FCA Venture Partners invests in companies poised to transform healthcare. We've backed over 50 companies building technology to improve patient care, reduce costs, and reshape healthcare.

Healthcare Investment Focus: 73.17%
Seed Investment Activity: 15.00%
Total Healthcare Investments: 60
Most Recent Healthcare Investment: February 23, 2026
Website: https://www.fcavp.com/

Decheng Capital

Decheng Capital is an investment firm that provides capital and strategic support to early-stage life science companies with revolutionary technologies and growth stage healthcare companies with strong market presence.

Healthcare Investment Focus: 72.16%
Seed Investment Activity: 0.00%
Total Healthcare Investments: 70
Most Recent Healthcare Investment: March 3, 2026
Website: https://www.decheng.com/

Amboy Street Ventures

We are the world’s first venture capital fund focused on Women’s Health & Sexual Wellbeing for all genders.

Healthcare Investment Focus: 70.00%
Seed Investment Activity: 14.29%
Total Healthcare Investments: 14
Most Recent Healthcare Investment: November 21, 2025
Website: https://www.amboystreet.vc/

BlueStone Venture Partners

BlueStone Venture Partners is a best-in-class life sciences venture capital fund capitalizing on the strength, creativity, and innovation found in entrepreneurial companies outside of the traditional investment hubs in the United States.

Healthcare Investment Focus: 70.00%
Seed Investment Activity: 0.00%
Total Healthcare Investments: 7
Most Recent Healthcare Investment: May 1, 2025
Website: https://www.bluestonevp.com/

Boutique Venture Partners

We are a team of hardcore scientists and clinicians who partner with authentic founders to create innovative and disruptive approaches that improve health and wellness.

Healthcare Investment Focus: 69.23%
Seed Investment Activity: 44.44%
Total Healthcare Investments: 18
Most Recent Healthcare Investment: February 23, 2026
Website: https://www.boutiquevc.com/

SR One

A biotechnology venture capital firm, partnering with founders and entrepreneurs to translate innovative science into medicines.

Healthcare Investment Focus: 67.77%
Seed Investment Activity: 1.40%
Total Healthcare Investments: 143
Most Recent Healthcare Investment: January 7, 2026
Website: https://www.srone.com/

Civilization Ventures

Our Civilization team comprises leaders in the life sciences sector, including c-suite stars, top academics and industry titans. All here to help you build the future.

Healthcare Investment Focus: 65.67%
Seed Investment Activity: 25.00%
Total Healthcare Investments: 44
Most Recent Healthcare Investment: March 9, 2026‍
Website: https://www.civilizationventures.com/

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Additions or Corrections?

We hope this list is helpful! If you see a mistake or would like to recommend a fund that we missed, please email the author directly at archie [at] betaboom.com. And sorry in advance if we missed your fund on our first go-round! I’m sure this is just the beginning.

How We Invest: At Beta Boom, we believe the hardest part of building a healthcare startup is not raising capital, but figuring out how to grow, navigate complexity, and deliver real outcomes.

We go beyond investing. We work hands-on with founders as an extension of their team, helping them scale solutions that improve access, affordability, and quality of care.

No cookie-cutter programs or generic advice. Just focused support, real partnership, and a shared commitment to building impactful healthcare companies.

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General Partner at Beta Boom

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